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Infinite Brain MR Images: PGGAN-based Data Augmentation for Tumor Detection

2019-03-29
Changhee Han, Leonardo Rundo, Ryosuke Araki, Yujiro Furukawa, Giancarlo Mauri, Hideki Nakayama, Hideaki Hayashi

Abstract

Due to the lack of available annotated medical images, accurate computer-assisted diagnosis requires intensive Data Augmentation (DA) techniques, such as geometric/intensity transformations of original images; however, those transformed images intrinsically have a similar distribution to the original ones, leading to limited performance improvement. To fill the data lack in the real image distribution, we synthesize brain contrast-enhanced Magnetic Resonance (MR) images—realistic but completely different from the original ones—using Generative Adversarial Networks (GANs). This study exploits Progressive Growing of GANs (PGGANs), a multi-stage generative training method, to generate original-sized 256 X 256 MR images for Convolutional Neural Network-based brain tumor detection, which is challenging via conventional GANs; difficulties arise due to unstable GAN training with high resolution and a variety of tumors in size, location, shape, and contrast. Our preliminary results show that this novel PGGAN-based DA method can achieve promising performance improvement, when combined with classical DA, in tumor detection and also in other medical imaging tasks.

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URL

http://arxiv.org/abs/1903.12564

PDF

http://arxiv.org/pdf/1903.12564


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